Detalhe da pesquisa
1.
Gut microbiome and metabolome profiling in Framingham heart study reveals cholesterol-metabolizing bacteria.
Cell
; 187(8): 1834-1852.e19, 2024 Apr 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38569543
2.
helixCAM: A platform for programmable cellular assembly in bacteria and human cells.
Cell
; 185(19): 3551-3567.e39, 2022 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36055250
3.
Chemically inducible split protein regulators for mammalian cells.
Nat Chem Biol
; 19(1): 64-71, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36163385
4.
Binding of the transcription activator-like effector augments transcriptional regulation by another transcription factor.
Nucleic Acids Res
; 50(11): 6562-6574, 2022 06 24.
Artigo
Inglês
| MEDLINE | ID: mdl-35670660
5.
A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells.
Nat Chem Biol
; 16(5): 513-519, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31907374
6.
Polarized displacement by transcription activator-like effectors for regulatory circuits.
Nat Chem Biol
; 15(1): 80-87, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30455466
7.
Design of fast proteolysis-based signaling and logic circuits in mammalian cells.
Nat Chem Biol
; 15(2): 115-122, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30531965
8.
Locked and proteolysis-based transcription activator-like effector (TALE) regulation.
Nucleic Acids Res
; 44(3): 1471-81, 2016 Feb 18.
Artigo
Inglês
| MEDLINE | ID: mdl-26748097
9.
Transcription activator-like effector-mediated regulation of gene expression based on the inducible packaging and delivery via designed extracellular vesicles.
Biochem Biophys Res Commun
; 484(1): 15-20, 2017 02 26.
Artigo
Inglês
| MEDLINE | ID: mdl-28111345
10.
Designable DNA-binding domains enable construction of logic circuits in mammalian cells.
Nat Chem Biol
; 10(3): 203-8, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24413461
11.
DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency.
Nucleic Acids Res
; 40(4): 1879-89, 2012 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22021385
12.
Subunits of an E3 Ligase Complex as Degrons for Efficient Degradation of Cytosolic, Nuclear, and Membrane Proteins.
ACS Synth Biol
; 13(3): 792-803, 2024 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38404221
13.
Concatenated Coiled-Coil Tag for Highly Efficient, Small Molecule-Inducible Upregulation of Endogenous Mammalian Genes.
Methods Mol Biol
; 2577: 197-209, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36173575
14.
Engineering and Rewiring of a Calcium-Dependent Signaling Pathway.
ACS Synth Biol
; 9(8): 2055-2065, 2020 08 21.
Artigo
Inglês
| MEDLINE | ID: mdl-32643923
15.
Correction to Subunits of E3 Ligase Complex as Degrons for Efficient Degradation of Cytosolic, Nuclear and Membrane Proteins.
ACS Synth Biol
; 2024 Apr 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38678638
16.
CRISPRa-mediated FOXP3 gene upregulation in mammalian cells.
Cell Biosci
; 9: 93, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31832140
17.
Designed Transcriptional Regulation in Mammalian Cells Based on TALE- and CRISPR/dCas9.
Methods Mol Biol
; 1772: 191-203, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29754229
18.
Benchmarking of TALE- and CRISPR/dCas9-Based Transcriptional Regulators in Mammalian Cells for the Construction of Synthetic Genetic Circuits.
ACS Synth Biol
; 5(10): 1050-1058, 2016 10 21.
Artigo
Inglês
| MEDLINE | ID: mdl-27344932
19.
A bistable genetic switch based on designable DNA-binding domains.
Nat Commun
; 5: 5007, 2014 Sep 29.
Artigo
Inglês
| MEDLINE | ID: mdl-25264186